By Errol C Friedberg
With a Foreword through Sydney Brenner (Nobel laureate in body structure or drugs, 2002)
This biography information the lifetime of Paul Berg (Emeritus Professor at Stanford University), tracing Berg's lifestyles from beginning, in 1926, to the current, with detailed emphasis on his huge, immense clinical contributions, together with being the 1st to enhance expertise that resulted in gene cloning technological know-how. In 1980, Berg bought a Nobel Prize in chemistry for this work.
In addition to his contributions within the study laboratory, Berg orchestrated and oversaw a historical assembly at Asilomar, California that based on a threatening controversy surrounding the conception through a few of the damaging power of recombinant DNA know-how. This assembly did a lot to prevent this controversy and to install position the law of recombinant DNA paintings, hence placing fears to rest.
The recombinant DNA controversy was once a old consequence of the invention of gene cloning. particularly, it represented a paramount instance of clinical foresight and due diligence through the clinical neighborhood, instead of via regulatory entities within the usa and lots of different international locations. the last word popularity of gene/DNA cloning resulted in a brand new period of contemporary biology that flourishes to the present.
This publication is aimed essentially at scientists and people in education. The ebook strives to easily supply details for the overall reader, yet isn't particularly adapted for a normal interpreting audience.
While many books disguise the recombinant DNA controversy, none have satisfactorily addressed this old interval and are usually contradictory in regards to the many who is, where's, and why's concerned. also, the nice majority of those have been written by way of non-scientists. This biography of Paul Berg offers entry to various archived letters and files at Stanford college now not formerly addressed, and to the chronology of occasions as recalled and documented through him, in addition to different key personalities, a lot of whom have been interviewed.
- Part I:
- Growing Up in Brooklyn
- The crucial Paul Berg
- College — and international conflict II
- Western Reserve University
- Part II:
- Washington college, St. Louis
- Discovering move RNA
- Stanford college — and Its Refurbished division of Biochemistry
- Transcription and Translation: New Directions
- Part III:
- Making Recombinant DNA — the 1st Faltering Steps
- Making Recombinant DNA — a tremendous Breakthrough
- EcoRI limit Endonuclease — an enormous Breakthrough
- “Coincidence is the note We Use after we cannot See the Levers and Pulleys”
- Yet one other Stanford Contribution
- Part IV:
- An old assembly in Hawaii
- The Recombinant DNA Controversy
- A Momentous Gordon learn Conference
- Making Recombinant Molecules with Frog DNA
- The Controversy Heats Up
- Asilomar II
- The Dissenters: a special element of View
- The Aftermath
- Legislative and Revisionist demanding situations to Recombinant DNA
- Asilomar II — classes Learned
- Part V:
- The Nobel Prize in Chemistry
- Commercializing the Technology
- Life is going on
- The “Retirement” Years
- Public coverage matters — and different Interests
- Personal Challenges
Readership: Researchers, graduate scholars, undergraduates in lifestyles sciences, medication and chemistry and lay public.
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Extra resources for A Biography of Paul Berg:The Recombinant DNA Controversy Revisited
A Biography of Paul Berg:The Recombinant DNA Controversy Revisited by Errol C Friedberg